Streptococcus suis (S. suis) is a gram-positive pathogen that poses a significant threat to swine producers worldwide. It is a major cause of antibiotic use in modern swine production. S. suis resides asymptomatic in the upper respiratory tract but can become pathogenic when it penetrates the mucosal barriers and enter the bloodstream, joints or central nervous system. This can lead to the development of various symptoms such as meningitis, endocarditis and even sudden death. To effectively combat S. suis, a multifactorial approach is required. Eastman, a leading provider of innovative solutions, offers a range of products to address this challenge.

The versatility of α-monoglycerides

One of the key components in Eastman’s solutions is the use of α-monoglycerides. These versatile molecules work independently of pH and are active along the gastrointestinal (GI) tract. By incorporating α-monoglycerides into the animal's diet, Eastman's solutions aim to strengthen the animal's defenses against S. suis​.​

Eastman Entero-Nova™ and Eastman Protaq™ Bond

Eastman Entero-Nova™ and Protaq™ Bond are customizable solutions developed by Eastman. Entero-Nova is applied via feed and Protaq Bond via water. These solutions are based on the synergy between organic acids and α-monoglycerides of short- and medium-chain fatty acids (SCFA and MCFA). By leveraging this synergy, these concepts can enhance the gut barrier, immune function and pathogen control.

Strengthening the gut barrier

S. suis can translocate across epithelial barriers, which can result in systemic inflammation and organ damage. The inclusion of α-monoglycerides of SCFAs (including butyric acid) and MCFAs helps strengthen the gut barrier. This, in turn, reduces the likelihood of S. suis entering the bloodstream, preventing the onset of systemic inflammation and associated complications.

Enhancing immune function

A robust immune system is crucial in combating S. suis infections. The synergistic effects of α-monoglycerides of SCFAs and MCFAs in Eastman's solutions contribute to enhancing immune function. This helps the animals mount a stronger defense against S. suis, ultimately reducing the severity of infections and associated complications.

A graph shows average daily gain among the treatment groups from starter phase to finisher

Controlling pathogens

Effective pathogen control is essential in mitigating the impact of S. suis. The combined action in Entero-Nova and Protaq Bond helps control the growth and proliferation of pathogens, including ​S. suis. This contributes to reducing the overall disease burden and promoting swine health and productivity.

Reducing antibiotic interventions​

By strengthening animal defenses against S. suis, Eastman's solutions can potentially reduce the need for antibiotic interventions. This is significant in the context of modern swine production, where antibiotic usage is a major concern. Minimizing antibiotic use promotes sustainable farming practices and helps address the issue of antibiotic resistance.

Consult Eastman sales and technical representatives

To learn more about Eastman's Protaq Bond and Entero-Nova solutions aimed at alleviating the impact of S. suis in swine herds, contact Eastman's sales and technical representatives. Our experts can provide detailed information about the application of Eastman's products, application recommendations, and their potential benefits in specific farming contexts.

Conclusion

Streptococcus suis poses a significant challenge to swine producers, necessitating a multifaceted approach for effective control. Eastman's holistic solutions, Entero-Nova and Protaq Bond, leverage the synergistic effects of α-monoglycerides of SCFAs (including butyric acid) and MCFAs to strengthen the gut barrier, enhance immune function and control pathogens. By incorporating these solutions, swine producers can improve animal health and productivity while reducing the need for antibiotic interventions.

Animal nutrition