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BioSustane applications​

Create formulations you trust

Eastman BioSustane™ SAIB NF helps formulators create better formulations with its versatile and multifunctional properties. Its ability to enhance tamper resistance, provide sustained release and improve bioavailability makes it invaluable in pharmaceutical development. By addressing common formulation challenges, BioSustane enables the development of safer, more effective, patient-friendly medications.

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Develop innovative
products

BioSustane is a versatile pharmaceutical ingredient that empowers formulators to develop innovative and effective products for patients. Its unique properties, such as enhancing tamper resistance and improving bioavailability, make it suitable for a wide range of applications.

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Abuse deterrence

BioSustane SAIB NF is a novel excipient designed to enhance abuse-deterrent properties in dosage forms, providing tamper resistance against common methods like crushing and dissolving in liquids. 

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Amorphous solid dispersion

Due to its highly hydrophobic properties, BioSustane can be used as a carrier for amorphous solid dispersions without hot-melt extrusion or spray drying. It can be formulated using traditional wet granulation techniques, improving bioavailability by preventing recrystallization of poorly water-soluble active pharmaceutical ingredients (APIs). 

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Depot* former

As a depot* former, BioSustane ensures controlled release of APIs, maintaining consistent therapeutic levels and improving patient compliance. This steady delivery reduces dosing frequency and side effects, enhancing the effectiveness of long-acting pharmaceuticals. 

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Sustained release

BioSustane provides sustained release of APIs, maintaining stable therapeutic levels and reducing the need for frequent dosing. This consistent delivery improves patient adherence, minimizes side effects, and enhances treatment efficacy, making it essential in pharmaceutical formulations. 

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Other applications

BioSustane applications can extend beyond sustained release and abuse deterrence. Public information suggests BioSustane SAIB NF could be used in radiopaque fiducial markers, ophthalmic formulations, topical composition and more.  

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*Eastman Chemical Company does not manufacture or market an injectable grade of BioSustane SAIB NF excipient. It is the responsibility of our customers to determine that their use of our product(s) is safe, lawful and technically suitable in their intended applications.

Have questions about BioSustane applications?


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