Formulation predictor

Accelerate formulation development with Eastman FastER.

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Develop formulations
faster

What is Eastman FastER?

Eastman FastER (formulation assistance for extended release) is a web-based tool that suggests a starting formulation for extended-release coatings for oral solid dosages. FastER uses a statistical algorithm developed by Eastman based on insights from several formulation studies carried out with a fairly water-soluble active pharmaceutical ingredient (API).

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Benefits for drug formulators

Pharmaceutical formulators spend a considerable amount of time and effort experimenting, analyzing and revising to develop new drug formulations. FastER provides access to starting point formulations tailored to the desired dissolution profile (drug release over a period of time), accelerating time to market. The suggested formulation contains the ratio of Eastman cellulose ester polymers to be used along with the coating percentage to achieve the desired dissolution.

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What are the starting formulations based on?

Eastman has conducted numerous formulation studies based on the design of experiments (DoE) principle. We determined that the results could be explained and modeled to help formulators in the development phase. Leveraging DoE formulation studies, Eastman built a predictive algorithm that provides starting formulations tailored to formulator inputs.

How accurate is the starting formulation?

Eastman FastER helps pharmaceutical formulators accelerate development timelines. While the tool suggests directionally correct formulations, factors like plasticizer type, ingredient amounts, coating equipment and conditions can affect dissolution.

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Which pharmaceutical ingredients are included?

FastER is a first-generation online tool based on several formulation studies conducted with one API. We are committed to working with our customers to improve and expand its capabilities to meet market needs.

Cellulose esters

At Eastman, we offer a diverse portfolio of cellulose esters that addresses a broad range of formulating challenges.

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Formulation predictor​

Develop formulations faster